About CEPCEB Introduction: The Frontier
of Research in Plant Cell Biology and Genomics, Systems-Based Approach
This
is an exciting time for plant biology. Plants are the basis of all life on Earth,
whether as components of natural ecosystems or as domesticated crops used for
food, feed and materials. After centuries of study, we are beginning to understand
the complex signals and biochemical networks that allow plants to rapidly and
exquisitely adapt to diverse environments as vital components of earth's biosphere.
The Center for Plant Cell Biology (CEPCEB) focuses on a diverse group of plants
and fungi that provide the foundation for all life on earth. Capitalizing on the
scientific momentum created by the genome sequencing of two important plants -
Arabidopsis and rice - CEPCEB seeks to develop a comprehensive understanding
of how plants function as whole organisms. The goal of this scientific challenge,
involving an interdisciplinary effort by engineers, plant biologists, plant pathologists,
chemists, physicists and computer scientists, is to apply the knowledge of how
plants respond to their dynamic environment toward manipulation of crop plants
safely and efficiently for better and more sustainable production. We are
inspired to transfer our excitement of plant cell biology to a new generation
of scientists who will extend research at our university around the world.
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Mission: The Center for Plant Cell
Biology at the University of California, Riverside
The Center
for Plant Cell Biology (CEPCEB) is the nation's first research center devoted
exclusively to plant cell biology. As part of the Institute
for Integrative Genome Biology at the University
of California, Riverside, the Center addresses
significant outstanding questions in plant biology by integrating genomic, bioinformatic,
cellular, molecular, biochemical, and genetic approaches. The Center synergizes
UCR's existing strengths in botany and plant sciences, in part by providing an
infrastructure that promotes interdisciplinary research and interaction among
researchers. The emerging experimental paradigm for addressing biological issues
is systems-based research, which uses new approaches in computational
biology and engineering to advance knowledge gained at the gene level into an
understanding of how organisms function as biological machines. To support this
work, CEPCEB has developed technology cores in cutting-edge disciplines: microscopy/imaging,
bioinformatics, and proteomics. In addition, CEPCEB has initiated high-throughput
methods to identify and characterize bioactive compounds from chemical libraries
that will allow precise temporal and spatial manipulation of specific plant processes.
These chemical genomics methods will greatly enhance more traditional genetic
approaches and provide exciting new avenues for the advancement of knowledge.
Thus, CEPCEB's mission is to unite scientists from diverse disciplines to utilize
innovative and integrated approaches that will lead to a comprehensive understanding
of the function of proteins and other important molecules within living plant
cells, within the context of the whole plant. The Center accomplishes this
mission by creating teams whose members conduct research using multidisciplinary
approaches applied to both model plant systems and important crop plants. Although
the Center is nucleated around plant biology, its infrastructure extends into
related areas of biological science and other disciplines when appropriate. The
interconnection between biology and various disciplines such as applied mathematics,
statistics, engineering, physics and chemistry is greatly stimulated as a result
of this infrastructure. These connections will open additional exciting new areas
for graduate student training. University
of California at Riverside Institute
for Integrative Genome Biology
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Opportunities for Graduate Training
CEPCEB
faculty provide students opportunities for training leading to the Ph.D. degree
in a number of graduate programs including: Plant Biology (Department
of Botany and Plant Sciences),
Genetics, Genomics
and Bioinformatics, Cell,
Molecular and Developmental Biology, Biochemistry
and Molecular Biology, Plant
Pathology, Microbiology,
and Engineering (Mechanical,
Electrical, and Computer
Science). Research in plant systems biology is possible for a broad spectrum
of topics that include:
- Cell architecture
- Intracellular protein
transport
- Cell-cell communication
- Signal transduction
- Cytoskeleton
- Cell
cycle control
- Mechanisms of gene inheritance and gene regulation
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- Responses to environmental change
- Meristem and organ development
- Pollination
- Responses
to environmental changes
- Responses to bacteria, fungi and insects
- Biosensor
development
- Computational biology
| Plant
Cell Biology/Chemical Genomics (NSF IGERT Program): For information
regarding graduate research training in plant cell biology/chemical genomics at
UCR's Center for Plant Cell Biology, please visit: NSF-funded
ChemGen IGERT (Integrative Graduate Education and Research Trainee) Program. Plant
Biology, Plant Genetics: Students usually spend five years earning
the Ph.D. degree in the Botany
and Plant Sciences Graduate Program. During the first two years, a student
takes courses and initiates the dissertation research. After course requirements
have been met and the student has passed written and oral qualifying examinations,
which include intensive coverage of the area of specialization, the student advances
to candidacy for the Ph.D. degree. The student then completes his or her research,
submits a written dissertation, and defends a thesis In addition to plant cell
biology, possible areas of study include: biochemistry and genetics; whole-plant
structure and function; ecology and the evolution of crop, ornamental and native
plants; the application of advances in these areas to crop productivity; and ethnobotany.
Genetics, Genomics and Bioinformatics: Students in
the Genetics, Genomics and Bioinformatics (GGB) Graduate Program have the opportunity
to complete a Ph.D. in Genetics
with an emphasis in Bioinformatics/Genomics. Undergraduate work includes biology,
biochemistry, genetics, molecular biology, calculus, general and organic chemistry,
and parametric and non-parametric statistics courses. Graduate course work focuses
on computational biology, bioinformatics and genomics. Students have the option
to take additional graduate course work according to their interests and research
program. Biochemistry and Molecular Biology: Students
in the Biochemistry
and Molecular Biology (BMB) Graduate Program earn a M.S. or Ph.D. degree that
emphasizes basic biochemistry with research specializations in the areas of molecular
biology, physical biochemistry, plant biochemistry and molecular biology, signal
transduction, molecular endocrinology, and biomedical research.
Professors
currently associated with the Center for Plant Cell Biology include several in
the core areas of plant cell biology and several others in related areas such
as electrical and mechanical engineering, computer science, and statistics. The
Center includes three academic coordinators in the areas of microscopy (Dr.
David Carter) bioinformatics (Dr. Thomas Girke)
and proteomics (Dr. Songqin Pan).
Three additional professors in core areas of plant cell biology are expected to
be recruited within the next four years.The Director of the Center is Dr.
Natasha V. Raikhel (Distinguished Professor, Ernst and Helen Leibacher Endowed
Chair) in the Department of Botany
and Plant Sciences.
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Opportunities
for Undergraduate Training
The Center for Plant Cell Biology
(CEPCEB) in association with the Institute
for Integrative Genome Biology (IIGB) at the University of California, Riverside
is committed to providing rewarding research experiences to undergraduate students.
As an NSF Research Experience for Undergraduates (REU) Site, CEPCEB brings research
experiences to students of two- and four-year colleges who have limited opportunity
to learn about the excitement and career options that research in plant cell biology
offers. Ten undergraduates will be accepted into the ten-week residential program.
The program will begin with a one-week workshop, in which students will be introduced
to techniques and approaches used for analysis of plant and plant fungal pathogen
cell function, including basic molecular biology, genomic and bioinformatic analyses,
and confocal microscopy methods used to study live cells. Students will then spend
nine weeks working with a faculty mentor and a graduate or postgraduate mentor
on a research project of their choice. Students will also participate in workshops
to enhance learning skills and professional development, and to discuss ethics
in science.
CEPCEB intends to establish a novel year-round education program
that will enhance the academic development of low income and minority students.
The underlying goals of our educational outreach programs are to encourage completion
of four-year degrees by underrepresented students and to present research plant
biology as a career option to young biologists for the benefit of future generations.
Information
on NSF Research Experiences for Undergraduates (REU) Program
2008-2009
UCR General Course Catalog
Information for Future Students
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Location
The Center
for Plant Cell Biology (CEPCEB) is currently located on the second and third floors
of Batchelor Hall on Eucalyptus Drive. The north end of the building was renovated
in Spring 2002 to construct Noel Keen Hall, which houses the UCR Core Instrumentation
Facility. A new Genomics Building will be erected by February 2009 on the corner of Eucalyptus and Citrus Drives. Some CEPCEB
faculty will relocate to this location.
UCR
Map (search for "Batchelor Hall" and "Keen, Noel Hall")
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